What are major challenges regarding the creation of digital ecosystems and decentralized industrial data spaces in the US, in Japan, in Korea or in Europe? What is the importance of international collaboration in building global data spaces? What are the different local and global strategies to create open, sovereign and sustainable digital ecosystems? Plattform Industrie 4. 0 collaborates with various international partners to shape the digital transformation of industry jointly. It invites its international partners to reflect on local and global challenges and their learnings in shaping open, sovereign and sustainable digital ecosystems as well as efforts to enhance the digitalization of industry. The panel highlights the importance of global efforts and emphasizes on the shift towards decentralized industrial data spaces.